2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-143956S
    Fluorofenidone impurity 1-d3
    Fluorofenidone impurity 1-d3 is the deuterium labeled Fluorofenidone impurity 1.
    Fluorofenidone impurity 1-d<sub>3</sub>
  • HY-131251
    Cetirizine 3-chloro impurity
    Cetirizine 3-chloro impurity is an impurity of Cetirizine 3-chloro.
    Cetirizine 3-chloro impurity
  • HY-112057
    Pseudoerythromycin A enol ether
    		99.48%
    Pseudoerythromycin A enol ether (LY267108) is a degradation product of Erythromycin. Pseudoerythromycin A enol ether has no significant antimicrobial activity.
    Pseudoerythromycin A enol ether
  • HY-114547
    PD 109488
    PD 109488 is a quinapril diketopiperazine metabolite.
    PD 109488
  • HY-N16477
    Ciceritol
    Ciceritol is a dietary fiber component/prebiotic targeting α-galactosidic linkage oligosaccharides. Ciceritol selectively promotes proliferation of beneficial bacteria like Bifidobacteria. Ciceritol is promising for research of gut microbiota-related diseases (e.g., irritable bowel syndrome, metabolic syndrome).
    Ciceritol
  • HY-W009713S
    3,4,5-Trimethoxyphenylacetic acid-d2
    3,4,5-Trimethoxyphenylacetic acid-d2 is the deuterium labeled 3,4,5-Trimethoxyphenylacetic acid. 3,4,5-Trimethoxyphenylacetic acid is a metabolite of Mescaline.
    3,4,5-Trimethoxyphenylacetic acid-d<sub>2</sub>
  • HY-78847
    2R,4S-Sacubitril
    		98.15%
    2R,4S-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
    2R,4S-Sacubitril
  • HY-12769S
    Mebeverine acid-d5
    Mebeverine acid-d5 (Mebeverine metabolite Mebeverine acid-d5) is the deuterium labeled Mebeverine Acid (HY-12769). Mebeverine acid is a secondary metabolite of the intestinal antispasmodic agent Mebeverine (HY-A0078). Mebeverine acid is generated by the hydrolysis of Mebeverine in the body and is considered a key circulating metabolite. Mebeverine acid is an important marker for oral Mebeverine.
    Mebeverine acid-d<sub>5</sub>
  • HY-135408
    Trimetazidine-N-oxide
    Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties.
    Trimetazidine-N-oxide
  • HY-13256AR
    Desmethyl Erlotinib (Standard)
    Antioxidant 1024 (Standard) is the analytical standard of Antioxidant 1024. This product is intended for research and analytical applications. Antioxidant 1024 (MD 1024) is an antioxidant agent and metal deactivator.
    Desmethyl Erlotinib (Standard)
  • HY-W744266
    9α,10α-Epoxyhexahydrocannabinol
    9α,10α-Epoxyhexahydrocannabinol is an active metabolite of delta 9-tetrahydrocannabinol. 9α,10α-Epoxyhexahydrocannabinol has anti-convulsant activity. 9α,10α-Epoxyhexahydrocannabinol reduces body temperature, prolongs pentobarbital-induced sleep, and exerts anticonvulsant activity against pentylenetetrazol-induced seizures in mice.
    9α,10α-Epoxyhexahydrocannabinol
  • HY-118472R
    Benazeprilat (Standard)
    Benazeprilat (Standard) is the analytical standard of Benazeprilat. This product is intended for research and analytical applications. Benazeprilat is an orally active and the active metabolite of benazepril, a carboxyl-containing ACE inhibitor with antihypertensive activity. Benazepril is a well-established antihypertensive agent, both in monoresearch and in combination with other classes of drugs including thiazide diuretics and calcium channel blockers. Benazepril is a first-line research in reducing various pathologies associated with CV risk and secondary end-organ damage.
    Benazeprilat (Standard)
  • HY-N17698
    Cyclogaleginoside B
    Cyclogaleginoside B (Cyc B) is a metabolize of Astragaloside IV (HY-N0431) by intestinal microbiota.
    Cyclogaleginoside B
  • HY-136347R
    3α-Hydroxy pravastatin sodium (Standard)
    3α-Hydroxy pravastatin sodium (Standard) is the analytical standard of 3α-Hydroxy pravastatin sodium. This product is intended for research and analytical applications. 3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin (HY-B0165A). Pravastatin is a competitive HMG-CoA reductase inhibitor.
    3α-Hydroxy pravastatin sodium (Standard)
  • HY-118844R
    Flumazenil acid (Standard)
    Flumazenil acid (Standard) is the analytical standard of Flumazenil acid. This product is intended for research and analytical applications. Flumazenil acid is a metabolite of Flumazenil. Flumazenil is a GABAA receptor antagonist.
    Flumazenil acid (Standard)
  • HY-113157
    Estrone 3-glucuronide
    Estrone 3-glucuronide is a dominant urinary metabolite of Estradiol (HY-B0141) and urinary marker for female fertile window prediction. Estrone 3-glucuronide can be used in combination with luteinizing hormone in ovulation prediction kits[2].
    Estrone 3-glucuronide
  • HY-129043R
    3-Formyl rifamycin (Standard)
    3-Formyl rifamycin (Standard) is the analytical standard of 3-Formyl rifamycin (HY-129043). This product is intended for research and analytical applications. 3-Formyl rifamycin is an acid degradation product of the broad-spectrum antibiotic Rifampicin (HY-B0272). 3-Formyl rifamycin forms via acid hydrolysis of Rifampicin in an acidic environment.
    3-Formyl rifamycin (Standard)
  • HY-133724R
    Vardenafil N-oxide (Standard)
    Vardenafil N-oxide (Standard) is the analytical standard of Vardenafil N-oxide. This product is intended for research and analytical applications. Vardenafil N-oxide is a N-Oxide impurity of Vardenafil (HY-B0442).
    Vardenafil N-oxide (Standard)
  • HY-100660A
    Cetirizine Impurity B dihydrochloride
    Cetirizine Impurity B dihydrochloride is an impurity of Cetirizine dihydrochloride. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
    Cetirizine Impurity B dihydrochloride
  • HY-131284
    (S)-Dehydro Venlafaxine
    (S)-Dehydro Venlafaxine is an inactive S-enantiomer of Dehydro Venlafaxine. Dehydro Venlafaxine is an impurity of Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a potent serotonin (5-HT) / norepinephrine (NE) reuptake dual inhibitor.
    (S)-Dehydro Venlafaxine
Cat. No. Product Name / Synonyms Application Reactivity